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EB-1 . CUBICIN ® (daptomycin for injection) for S. aureus Bacteremia Including Those With Known or Suspected Endocarditis . Anti-Infective Drugs
2006-4209S1-02-07-CUBIST-SUPPLEMENTAL.PPT - Search
cubicin
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bacteremia
including
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known
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endocarditis
anti-infective
Cell wall agents: Vancomycin-effective against MRSA, gram positive organisms in PCN allergic, caution with renal dosing Daptomycin-also effective against MRSA and VRE ...
Bugs and Drugs.ppt - Search
... Q12H Drug-drug interactions: Non-selective inhibitor of MAO Possible serotonergic or adrenergic interaction with anti-depressant medications (incidence < 1%) Daptomycin ...
Antibacterials2_Raasch.ppt - Search
drug-drug
non-selective
inhibitor
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adrenergic
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anti-depressant
medications
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... Disease Physician Consultation Criteria Non-Conformance Rate Caspofungin 100% (30 patients) 23% (no de-escalation to another agent with Candida albicans) Daptomycin 93% ...
FinalAntibioticStewardshipCC1008AzHHAGrayWightkin.ppt - Search
(A) MRSA has a high level of resistance to daptomycin (B) Daptomycin triggers parenchymal hemorrhage in lung tissue (C) Daptomycin diffuses poorly into the blood supply ...
hospital.ppt - Search
level
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triggers
parenchymal
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diffuses
poorly
blood
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... Promising alternative to vancomycin Attwood and LaPlante, Am J Health Sys Pharm, 2007 Televancin Spectrum of Activity Comparable to vancomycin, linezolid and daptomycin ...
bronze.ppt - Search
... Vancomycin Red Man Syndrome Individualized dosing Irritating to veins Other Antibiotics Azithromycin (Zithromax) Doxycycline Fluoroquinolones Carbapenems Daptomycin ...
Chpt-5.aspx - Search
vancomycin
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fluoroquinolones
carbapenems
... dysfunction Tunnel Cuffed Catheters : Bacteremia Tailored treatment MRSA : vancomycin, daptomycin if vancomycin allergy MSSA : cefazolin (Ancef) VRE : daptomycin Gram ...
Dialysis Basics.ppt - Search
Daptomycin . Tally, DeBruin. J Antimicrob Chemother. 2000;46:523-526. Louie et al. Antimicrob Agents Chemother. 2001;45:845-851. Cha et al. Antimicrob Agents Chemother ...
Daptomycin was bactericidal against both MSSA and MRSA by 24 h (decrease of 5.51 to 6.31 ±0.10 log 10 CFU/g). Nafcillin, vancomycin, and linezolid did not ...
DRB_MRSA.ppt - Search
... and GI (ingestion of infected animal) Candidemia Smallpox versus Chickenpox—degree of fever and early timing of systemic symptoms, stage of lesions Drugs: daptomycin ...
6.16.09 Peppercorn ID Board Review.ppt - Search
ingestion
infected
candidemia
smallpox
versus
degree
fever
early
timing
systemic
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lesions
In a first step, daptomycin aggregates in solution in the presence of a minimum of 1:1 calcium to daptomycin molar ratio. Then, daptomycin inserts into the membrane ...
BiosynthesisofNaturalProducts-2.ppt - Search
Infective Endocarditis Dr Mohamad Jarrah Cardiologest * Pelletier and Petersdorf criteria – 3 case categories: Definite – histologic evidence of endocardial ...
(5) Infective Endocarditis Internal.ppt - Search
infective
mohamad
jarrah
cardiologest
pelletier
petersdorf
criteria
definite
histologic
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endocardial
Daptomycin’s mechanism of action takes place at the bacterial cell membrane 4. Daptomycin causes renal failure in 4-7% of patients
Antimicrobial_Fellows_2011.ppt - Search
Anaphylaxis Patient “refuses” drug Can’t get the right levels Ease of dosing Daptomycin FDA approved in 2003 Depolarizes the cell membrane and is rapidly ...
Residents-antibiotic-Lecture.ppt - Search
anaphylaxis
patient
right
levels
approved
depolarizes
membrane
rapidly
Linezolid controversy Linezolid concerns Key messages: Linezolid Daptomycin (Cubicin) Killing of MRSA log10 colony-forming units/ml as a function of time in hours ...
MRSA More Pts More Rxs Rev 29Aug06.ppt - Search
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 DHS/PP Daptomycin (Cubicin) DHS/PP Antimicrobial: Question ...
Since 2000, only 3 new classes approved by FDA—effective largely against MRSA &VRE: streptogramins, linezolid, daptomycin; Apart from tigecycline, no new ...
fpic_antibioticusage2007_final.ppt - Search
PEDIATRIC HEMATOLOGY Unit 4: Part 3 Module 3 Prepared by: C. Sargo RN (EC) Reviewed by: Maj. Quinn RN (EC) REFERENCES C290- Nelson’s Essentials of Pediatrics C306 ...
u4_p3_m3.ppt - Search
pediatric
hematology
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sargo
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quinn
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c290-
essentials
pediatrics
Rybak MJ, et al. J Clin Microbiol 2008;46:2950–4 . Steinkraus G, et al. JAC 2007;60:788–944 . Vancomycin . Linezolid . Daptomycin . Wang G, et al. J Clin Microbiol 2006 ...
f20110113164916.ppt - Search
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